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# Childhood disadvantage carried a 26% higher rate of adult all-cause mortality
- URL: https://www.coios.me/childhood-disadvantage-carried-a-26-higher-rate-of-adult/
- Published: 2026-10-03T13:08:18.000Z
- Updated: 2026-10-03T17:37:18.000Z
- Description: A meta-analysis of 102 cohort studies covering about 8.5 million people in 24 countries found adult all-cause mortality 26% higher for those whose fathers held the lowest-ranked occupations, with a relative index of inequality of 2.33 for childhood economic circumstances.
- Author: Daniel Ryan
- Tags: Healthcare today, Health funding and inequalities, Revisions and new sources, World, #peer-reviewed, #confirms, #item, #source-2026-10

Researchers pooled 102 observational cohort studies, covering roughly 8.5 million participants across 24 countries, on childhood socioeconomic circumstances and mortality after age 18\. Disadvantage was associated with higher mortality in 82% of 474 estimates, and the pooled hazard ratio for father's occupation was 1.26 (95% CI 1.18-1.35), equivalent to 181 excess deaths per 100 000 per year. Relative indices of inequality were 2.33 for economic circumstances and 2.28 for parental education, and cause-specific associations were strongest for respiratory mortality (HR 1.70-1.85) and lung cancer (HR 1.52).

*Why it is interesting: Puts a standardised figure on the adult mortality gap associated with childhood circumstances, across world regions and risk-of-bias strata.*

Source

[The Lancet Public Health, 1 October 2026](https://doi.org/10.1016/s2468-2667%2826%2900187-8?ref=coios.me)

DOI

10.1016/s2468-2667(26)00187-8

Type

Peer-reviewed article

Design

Systematic review and meta-analysis of 102 observational cohort studies, \~8.5 million participants, 24 countries, searched to May 2026

Verdict

Confirms prior evidence

Driver

[Health funding and inequalities](https://www.coios.me/d-health-inequality/)

Driver

[Revisions and new sources](https://www.coios.me/d-data-sources/)