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# Particulate matter shows no overall association with venous thromboembolism
- URL: https://www.coios.me/particulate-matter-shows-no-overall-association-with-venous/
- Published: 2026-09-23T12:45:03.000Z
- Updated: 2026-09-23T21:35:17.000Z
- Description: An updated meta-analysis of 19 observational studies covering more than 4.5 million people found no significant overall association between long-term particulate exposure and venous thromboembolism, with a modest one appearing only among studies reporting in the same units.
- Author: Daniel Ryan
- Tags: Healthcare today, Environment: air, heat, cold, World, #peer-reviewed, #refines, #item, #source-2026-09

The review pooled 19 observational studies of ambient particulate matter and venous thromboembolism covering over 4.5 million participants, harmonising estimates to increments of 10 micrograms per cubic metre. Overall long-term associations were not significant for PM2.5 (HR 1.42, 95% CI 0.88-2.28) or PM10 (HR 1.18, 0.85-1.64), both with heterogeneity above 96%. Restricting to studies that natively reported in those units gave PM2.5 a hazard ratio of 1.07 (1.01-1.14) with no heterogeneity at all, and short-term exposures showed no association.

*Why it is interesting: The result turns on how exposures were harmonised rather than on the underlying data, which is a caution about how air pollution estimates are assembled.*

Source

[Thrombosis and Haemostasis, 21 September 2026](https://doi.org/10.1055/a-2945-4974?ref=coios.me)

DOI

10.1055/a-2945-4974

Type

Peer-reviewed article

Design

Systematic review and random-effects meta-analysis of 19 observational studies, >4.5 million participants

Verdict

Refines prior evidence

Driver

[Environment: air, heat, cold](https://www.coios.me/d-environment/)