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# Real spending on high-cost 'high-impact' medicines in Catalonia rose about 30%, 2019–2024
- URL: https://www.coios.me/real-spending-on-high-cost-high-impact-medicines-in/
- Published: 2026-11-02T12:55:17.000Z
- Updated: 2026-11-02T17:27:18.000Z
- Description: Nominal spending on high-impact medicines in Catalonia rose from €1.10 billion in 2019 to €1.69 billion in 2024.
- Author: Daniel Ryan
- Tags: Data, models and systems, What linked data reveals, Health systems and access, Spain, #peer-reviewed, #confirms, #item, #source-2026-10, #score-55

This retrospective study used linked registry and billing data on Catalan spending on high-impact medicines, 2019–2024\. Spending rose 53% nominally and about 30% after inflation, while patients treated rose from 215,182 to 327,455\. The top 10 medicines accounted for 43% of expenditure and 30% of treated patients. Managed access measures covered 155 of the 208 indications newly reimbursed in 2022–2024\. Agreements with manufacturers held 2024 spending on that year's new indications to €23.6 million, a quantified €7 million saving. The design is descriptive, and savings from several agreements and from prescribing restrictions could not be quantified.

*Why it is interesting: Overall spending grew with patient numbers while spending per treated patient fell. It shows which agreements a regional payer used, such as discounts and spending caps, and in which disease areas.*

Source

[Health Policy OPEN, 31 October 2026](https://doi.org/10.1016/j.hpopen.2026.100189?ref=coios.me)

Paper

High-impact medicines, system sustainability and the role of access management: evidence from Catalonia

Authors

Lizano Gispert E, Gay D, Fontanet M, Gasol M, Clopes A, Vallano A

DOI

10.1016/j.hpopen.2026.100189

Full text

[Open copy](https://pmc.ncbi.nlm.nih.gov/articles/PMC13720820/?ref=coios.me) (open-access copy, PubMed Central)

Type

Peer-reviewed article

Design

Retrospective analysis of Catalan health service registry and billing data, high-impact medicine expenditure 2019-2024 and newly reimbursed indications 2022-2024

Verdict

Confirms prior evidence

Driver

[What linked data reveals](https://www.coios.me/d-linked-data/)

Driver

[Health systems and access](https://www.coios.me/d-health-systems/)