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# Ultra-processed food intake tracks higher mortality across 51 prospective cohorts
- URL: https://www.coios.me/ultra-processed-food-intake-tracks-higher-mortality-across/
- Published: 2026-09-23T13:12:00.000Z
- Updated: 2026-09-23T21:35:35.000Z
- Description: A dose-response meta-analysis of 51 prospective cohorts covering 8.8 million adults found ultra-processed food intake associated with all-cause mortality (HR 1.18) and cardiovascular events (HR 1.24), on evidence the authors themselves rate low to moderate.
- Author: Daniel Ryan
- Tags: Behavioural science, Diet and physical activity, Obesity, diabetes and the GLP-1 drugs, World, #peer-reviewed, #confirms, #item, #source-2026-09

The review pooled 51 prospective cohort studies of 8,819,894 adults whose ultra-processed food intake was measured by food frequency questionnaires, 24-hour recalls or dietary history, against seven chronic disease outcomes and death. Highest against lowest intake was associated with all-cause mortality (HR 1.18, 95% CI 1.10-1.26), cardiovascular events (HR 1.24), overweight or obesity (HR 1.23) and metabolic syndrome or diabetes (HR 1.24). Each additional 100 g a day was associated with 3% higher all-cause mortality (HR 1.03, 95% CI 1.02-1.05), and the authors grade the evidence no better than moderate certainty.

*Why it is interesting: It puts a figure on the association per 100 g a day across the largest cohort base yet assembled, while its own authors decline to call the evidence strong.*

Source

[Family medicine and community health, 22 September 2026](https://doi.org/10.1136/fmch-2026-003925?ref=coios.me)

DOI

10.1136/fmch-2026-003925

Type

Peer-reviewed article

Design

Dose-response meta-analysis of 51 prospective cohort studies, 8,819,894 adults, searched to April 2026

Verdict

Confirms prior evidence

Driver

[Diet and physical activity](https://www.coios.me/d-diet-activity/)

Driver

[Obesity, diabetes and the GLP-1 drugs](https://www.coios.me/d-obesity-diabetes/)