COIOS
Medical Item refines agency

Post-mortem investigation traces nearly four in five stillbirths to asphyxia or hypoxia

Investigation of 8,500 stillbirths and child deaths in seven high-mortality countries, using minimally invasive tissue sampling, laboratory testing and verbal autopsy, attributed 79.1% of stillbirths to perinatal asphyxia or hypoxia.

The Child Health and Mortality Prevention Surveillance network investigated 8,500 deaths among stillbirths and children under five in seven high-mortality countries using minimally invasive tissue sampling, laboratory testing, and verbal autopsy. Stillbirths were predominantly attributed to perinatal asphyxia or hypoxia (79.1%), frequently with maternal hypertensive disorders, placental abnormalities, and chorioamnionitis. The findings demonstrate how laboratory confirmation and standardised investigation methods identify specific preventable causes that conventional vital registration and verbal autopsy alone cannot capture.

Why it is interesting: Reveals how cause-of-death methodology changes attribution patterns and precision in high-mortality settings where most child deaths occur.

Source
Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002), 2026-09-10
DOI
10.15585/mmwr.ss7506a1
Type
Agency report
Design
Population-based surveillance with laboratory confirmation, seven countries, 2016-2024, n=8,500 deaths investigated
Verdict
Refines prior evidence
Development
How deaths are counted and attributed, and how much the method changes the answer