- 12 posts this week
- 16 drivers moved
- 3 trackers refreshed
- Releases this week
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Official figures
Where the evidence stands
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building mixedWhether cardiovascular mortality has stopped falling, and whyNo papers yet
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emerging strengtheningWhether machine learning predicts mortality better than the models we haveNo papers yet
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building strengtheningHow much official statistics revise their own past, and what it does to conclusionsNo papers yet
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established mixedWhat is happening to deaths from alcohol, drugs and suicideNo papers yet
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established strengtheningWhether inequalities in health and length of life are widening, and where
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emerging strengtheningWhat delayed care and waiting times cost in livesNo papers yet
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building strengtheningWhat linked registries are making it possible to know about whole populationsNo papers yet
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emerging mixedWhat wearables and digital biomarkers add to how we measure healthNo papers yet
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contested mixedHow well mortality can be forecast, and by whomNo papers yet
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contested mixedWhether dementia is becoming more or less common, and whether we can tellNo papers yet
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established steadyInfectious disease and pandemics: what they now cost in deaths, and how well we are defendedNo papers yet
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emerging strengtheningWhether genomic risk prediction is good enough to use on whole populations
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established steadyHow much isolation and loneliness actually shorten lives
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building steadyHow societies are paying for and providing care for older people
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contested mixedEarly-onset cancer, rising or better found
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building strengtheningWhat GLP-1 drugs are doing to population health, and who is actually taking them
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Item new preprint
Mortality from secondary lung cancer rose 17.5% above 2000 levels in the US by 2024
Secondary malignant neoplasm of the lung (C78.0) recorded on death certificates rose from 7.22 per 100,000 population in 2008 to 11.38 in 2024, 17.5% above 2000 levels, with disproportionate increases among adults aged 25–34 years (70.5%).
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Item confirms preprint
Sub-Saharan African family carers report physical, emotional and financial burden
A scoping review of 15 studies found that family caregivers of older adults with chronic life-limiting illnesses in Sub-Saharan Africa reported physical exhaustion, emotional distress, financial hardship and social isolation, alongside minimal formal health system support.
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Item refines peer-reviewed
Healthy working life expectancy at 50 averaged 11 years across 28 countries
In a 28-country cohort of 175,318 adults aged 50 and over, healthy working life expectancy at 50 was 10.98 years, 9.82 for women and 12.36 for men, with stroke associated with a 5.49-year reduction and higher health spending, governance quality and flexible work arrangements with longer spans.
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Item new preprint
Long-run mortality from tropical cyclones concentrates in socially vulnerable counties
Among high-vulnerability counties in Texas, tropical cyclone exposure was associated with elevated all-cause mortality persisting long after landfall, whereas the effect in lower-vulnerability counties was not statistically significant.
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Item confirms peer-reviewed
Social role participation shows dose-response association with lower systemic inflammation
Greater social role participation was associated with lower systemic inflammation, with a graded pattern showing progressively stronger benefits across increasing levels of social integration compared to isolation.
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Item refines preprint
Chronic loneliness associates with worse health and functioning in older age
Chronic loneliness was longitudinally associated with worse general health, functional capacity and mental wellbeing in 4,090 older English adults, with isolation patterns showing reversible effects on cognition and mental health.
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Item confirms peer-reviewed
Home-based care use varies across Japan's municipalities despite universal insurance
Home-based long-term care services in Japan show significant geographic clustering and variation despite universal insurance coverage, associated with municipal characteristics including financial strength and care provider availability.
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Item refines peer-reviewed
Polygenic score for osteoporosis shows modest discrimination gain in Japanese adults
A Japanese-ancestry polygenic score for ultrasound-defined osteoporosis added little to discrimination beyond age and sex, but quintile stratification gave incidence rate ratios of 1.42 in the lowest and 0.70 in the highest quintile over a mean 3.5 years of follow-up.
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Item refines peer-reviewed
Early-onset colorectal cancer shows distinct molecular profile but mixed survival
A scoping review of 46 studies from 22 countries found early-onset colorectal cancer (≤50 years) had more MSI/dMMR tumours and less BRAF V600E than late-onset disease, while survival differences varied across populations and tracked mainly with stage at presentation.
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Item refines peer-reviewed
Weight loss drives bone loss through endocrine, nutritional and mechanical mechanisms
Weight loss raises bone turnover and lowers bone mineral density via endocrine, nutritional, mechanical and microbiota-mediated pathways, with greater loss in older and lean adults and after severe caloric restriction such as with GLP-1 drugs or bariatric surgery.
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Releases this week
Next seven days: ONS weekly deaths (Wed 16); Eurostat excess mortality (Wed 16); ONS monthly deaths (Thu 17); UKHSA all-cause mortality surveillance (Thu 17). Full calendar