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Health todayMental health refines
Stressful life events in clinical notes associated with mental disorders and frailty
More types of stressful life event in 39.7 million Finnish clinical notes were associated with anxiety, depression and frailty.
Preprint · not peer-reviewed -
Data, models and systemsValue in health confirms
One-time CKD screening at age 55 in Finland: a lifetime cost-effectiveness model
Modelled one-time CKD screening of Finns aged 55, plus SGLT2i and RAASi treatment, cost €6,478 per quality-adjusted life year.
Peer-reviewed -
Health todayCancer refines
Smoking status and survival across solid cancers in a Finnish two-hospital cohort
Five-year overall survival was 71% in never smokers, 58% in former smokers and 49% in current smokers.
Peer-reviewed -
Tomorrow's worldSlowing ageing itself refines
Short telomeres, not epigenetic or proteomic ageing, raise interstitial lung disease risk
Of six ageing measures tested against six immune-mediated diseases, only longer leukocyte telomeres lowered interstitial lung disease risk.
Preprint · not peer-reviewed -
Data, models and systemsAI in medicine refines
Polygenic scores add most to prediction where clinical risk is already low
Across 150 diseases in 900,000 UK Biobank and FinnGen participants, polygenic scores added most in metabolic, cardiovascular, autoimmune and neurological disease, and added little for genitourinary and respiratory conditions.
Preprint · not peer-reviewed
