-
Data, models and systemsValue in health confirms
Lecanemab and donanemab for early Alzheimer's disease are not cost-effective in China
A lifetime Markov model found that neither lecanemab nor donanemab was cost-effective at current Chinese prices, from either perspective.
Peer-reviewed -
Behavioural scienceInfection and pandemics refines
Antimicrobial resistance in Chinese bloodstream infections over a decade, 2014 to 2023
Across 76,211 Chinese bloodstream isolates, ESBL-producing E. coli fell to 47.4% and carbapenem-resistant K. pneumoniae rose to 14.9%.
Peer-reviewed -
Data, models and systemsValue in health confirms
Lecanemab for early Alzheimer's disease in China exceeds the cost-effectiveness threshold
Lecanemab added 1.24 QALYs in early Alzheimer's disease in China, but cost 372,609 yuan per QALY, above the threshold.
Peer-reviewed -
Health todayDementia refines
Eating difficulty marks functional vulnerability rather than triggering cognitive decline
In four ageing cohorts, new eating difficulty was associated with higher dementia-indicator risk, but tooth loss showed little adjusted association.
Peer-reviewed -
Health todayCancer refines
HPV-attributable fraction in oropharyngeal cancer rose in seven countries over a decade
Central testing of 6,043 head and neck cancer specimens found HPV attributability in oropharyngeal cancer rose in all seven countries.
Peer-reviewed -
Health todayFrailty and multimorbidity refines
Plant-based diet indices and frailty in 8,628 older adults across three ageing cohorts
Higher overall plant-based scores were associated with lower frailty risk (ORs 0.71-0.80), unhealthful scores with higher risk (1.24-1.41).
Peer-reviewed -
Health todayCancer refines
Smaller colorectal tumours linked to nodal metastasis risk and worse survival in subgroups
In 10,513 colorectal cancer patients, smaller tumour diameter raised predicted lymph node metastasis risk and, below 3 cm, mortality.
Peer-reviewed -
Health todayObesity, diabetes and GLP-1 refines
Weight loss in impaired glucose tolerance went with fewer deaths over 34 years
In 540 Chinese adults with impaired glucose tolerance, a weight loss of 5% or more over six years carried a hazard ratio for death of 0.67 against no weight loss.
Peer-reviewed -
Data, models and systemsValue in health new
Modelled hepatitis B cure is cost-effective under USD46,642 a course in the US
A Markov model estimated that a hepatitis B cure regimen working in 30% of patients would be cost-effective at a one-off price below USD46,642 in the US.
Peer-reviewed -
Health todayHeart and stroke refines
Door-to-balloon under 60 minutes linked to lower mortality only in higher-risk STEMI
Among 4,513 STEMI patients in China, a door-to-balloon time over 60 minutes carried 1.69x the three-year mortality in those at higher risk on admission, but no difference at lower risk.
Peer-reviewed -
Data, models and systemsHealth systems and access new
Later-born Chinese older adults spend more years happy, with widening education gaps
Analysis of the Chinese Longitudinal Healthy Longevity Survey from 2002 to 2018 found that each later-born cohort of older adults spent a higher proportion of its remaining life happy.
Peer-reviewed -
Health todayCancer new
Air pollution before surgery was associated with higher mortality in gastric cancer
In 4,441 patients operated on for stage I-III gastric cancer in China, each standard-deviation rise in PM2.5 before surgery carried 15% higher all-cause mortality and 31% higher gastric cancer mortality.
Peer-reviewed
