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Plant-based diet indices and frailty in 8,628 older adults across three ageing cohorts

Higher overall plant-based scores were associated with lower frailty risk (ORs 0.71-0.80), unhealthful scores with higher risk (1.24-1.41).

Plant-based dietary patterns and frailty were examined in 8,628 older adults from the CLHLS, HRS and ELSA cohorts. Diet indices were derived from cohort-specific food-group data, and frailty from a multidomain deficit-accumulation index. Higher overall plant-based diet index was associated with lower frailty risk in all three cohorts (ORs 0.71-0.80). The unhealthful index was associated with higher risk (ORs 1.24-1.41); the healthful index was inversely associated only in ELSA. Network analysis showed nuts, vegetables and plant oils predominantly inversely associated with several frailty domains. Between-person dietary differences showed stronger associations than within-person changes, which limits inference about changing diet.

Why it is interesting: Diet quality, not plant content alone, is associated with frailty across three countries. The weak within-person signal shows how much of the association rests on differences between people.

Source
Age and Ageing, 21 October 2026
Paper
Plant-based dietary patterns and frailty in older adults: a multicohort longitudinal study with within-between decomposition and network analysis
Authors
Lin J, Zhang J, Hu B, Geng L
DOI
10.1093/ageing/afag304
Type
Peer-reviewed article
Design
Multicohort longitudinal observational analysis, 8,628 older adults in CLHLS, HRS and ELSA plus 10,821 in SHARE; generalised linear mixed models with within-between (Mundlak) decomposition, spline and network analysis
Verdict
Refines prior evidence
Driver
Frailty and multimorbidity
Driver
Diet, exercise and sleep
Driver
Slowing ageing itself

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