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Frailty at 50 linked to shorter healthy working life expectancy across 33 countries

In 180,314 adults from five harmonised ageing cohorts, healthy working life expectancy at age 50 was 11.87 years for robust participants, 7.34 years for pre-frail and 3.77 years for frail.

Healthy working life expectancy (HWLE) was estimated in 180,314 adults aged 50+ from HRS, ELSA, SHARE, MHAS and CHARLS. These five harmonised cohorts covered 33 countries; multistate Markov models used self-rated health, paid work and death. Using a cumulative deficit Frailty Index, HWLE at 50 was 11.87 years robust, 7.34 pre-frail, 3.77 frail. Pre-frail participants had 4.53 fewer years and frail participants 8.11 fewer years than robust participants. Men had longer HWLE than women only in the robust and pre-frail groups. Education, non-smoking and favourable national indicators accompanied longer HWLE, though a healthy worker effect may inflate estimates.

Why it is interesting: Separates health status from work participation and puts a figure on the working years lost with frailty. The country comparisons are ecological, and the national indicators used overlap heavily.

Source
Journal of Global Health, 19 October 2026
Paper
Frailty and healthy working life expectancy: a multicohort modelling study
Authors
Shui Y, Zhu J, Huang Z, You H, Gao J
DOI
10.7189/jogh.16.04338
Full text
Open copy (open-access copy, PubMed Central)
Type
Peer-reviewed article
Design
Multistate discrete-time Markov modelling of five harmonised ageing cohorts, 180,314 participants aged 50+ across 33 countries
Verdict
New finding
Driver
Frailty and multimorbidity
Driver
What linked data reveals
Free full text
Free to read at the publisher
Abstract — the authors' own words, CC BY

Background

Raising the retirement age and extending working years have become key strategies for many countries to mitigate the challenges of global population ageing. However, the association of frailty, a dynamic and reversible clinical condition, with healthy working life expectancy (HWLE) remains unclear. Methods

We used data from five harmonised health and retirement cohorts from across 33 countries, from which we tracked participants aged ≥50 years from baseline until their last available data point or death. Using this data, we evaluated frailty through the Frailty Index based on the cumulative deficit model, which classifies frailty status as robust, pre-frail, or frail. Then, we used discrete-time multistate Markov models to explore the association between frailty and HWLE, and further stratified our analyses by individual and country-level factors. Results

Among 180,314 participants, HWLE at the age of 50 years was 11.87 years (95% confidence interval (CI) = 11.74-12.00) for participants in the robust group, 7.34 years (95% CI = 7.19-7.50) for participants in the pre-frail group, and 3.77 years (95% CI = 3.57-3.97) for participants in the frail group. Compared with participants in the robust group, HWLE was 4.53 years shorter for those in the pre-frail group (Bonferroni-adjusted 95% confidence interval (95% CI BA ) = -4.76, -4.29) and 8.11 years shorter for those in the frail group (95% CI BA = -8.38, -7.84). Men had longer HWLE than women in the robust and pre-fail groups. Higher educational attainment and current non-smoking, as well as favourable national economic and political factors, were associated with longer HWLE across frailty strata. Conclusions

While frailty was generally associated with shorter HWLE at the age of 50 years, individual and country-level inequalities were also evident across frailty statuses. These results highlight a need to integrate targeted frailty prevention and intervention programmes with broader initiatives aimed at fostering national economic and political development, thereby promoting healthier, voluntary, and supported work participation in later life.

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