COIOS
Healthcare today Item new peer-reviewed

Higher particulate exposure before surgery tracked worse gastric cancer survival in China

In 4,441 patients who had radical surgery for stage I-III gastric cancer in Zhejiang, China, each standard-deviation rise in pre-surgery PM2.5 exposure was associated with 15% higher all-cause mortality and 31% higher gastric cancer-specific mortality.

A hospital-based cohort of 4,441 patients treated by radical surgery for stage I-III gastric cancer in Zhejiang between 2012 and 2022 linked modelled residential PM2.5 exposure over the 36 months before surgery to mortality after a median 3.83 years of follow-up. Each standard-deviation rise in PM2.5 carried an adjusted hazard ratio of 1.15 for all-cause death and 1.31 for gastric cancer-specific death, and the authors estimate 29.2% of all-cause deaths would be attributable to PM2.5 above the WHO 2021 guideline.

Why it is interesting: Places air pollution as a prognostic factor after a cancer diagnosis, not only as a determinant of who gets the disease.

Source
Environmental Research, 20 September 2026
DOI
10.1016/j.envres.2026.125689
Type
Peer-reviewed article
Design
Hospital-based cohort, 4,441 stage I-III gastric cancer patients after radical surgery, Zhejiang, China, 2012-2022, median follow-up 3.83 years
Verdict
New finding
Driver
Cancer
Driver
Environment: air, heat, cold
Driver
Forecasts and their track record