This study examined continued surveillance mammography and second primary breast cancer stage in older breast cancer survivors. This US retrospective cohort included 9,888 women with non-metastatic breast cancer diagnosed at 67 or older in 2004–2008. All had a surveillance mammogram about 5 years after diagnosis, and 80.3% were continuing surveillance at cohort entry. Cause-specific hazard models with inverse probability of treatment weighting estimated stage-specific risk, with follow-up to December 2021. Advanced second primary cancer reached 1.65% with continued surveillance and 2.15% without (hazard ratio 0.76, 95% CI 0.46–1.26). Findings were similar by hormone receptor status, but advanced second cancers were rare and the confidence interval was wide.
Why it is interesting: Surveillance mammography is common among older survivors, yet its benefit at this age is uncertain. Here the absolute risk of advanced second cancer was low whether or not women continued surveillance.
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