COIOSDeep risk insights through multi-disciplinary research across the globe
cake and macaroon on plate
Behavioural science

Social connection

Isolation, loneliness and mortality: what the evidence shows, how far the relationship is causal, and what interventions have shown.

Where the evidence stands

Socially isolated people have roughly a quarter to a third higher mortality than the well connected, across pooled prospective studies, and loneliness carries a similar excess. The association is one of the most replicated in social epidemiology. What is contested is how much of it is causal. Isolation and poor health cause each other, the studies are observational, and the effect shrinks when baseline health is properly measured. Intervention trials have shown that loneliness can be reduced. None has been large enough or long enough to show an effect on mortality. Public health bodies have moved nonetheless. A US Surgeon General's advisory in 2023 and a WHO commission in 2025 both treated social connection as a determinant of health on the scale of smoking. That is a policy judgement running ahead of the causal evidence, which is neither unusual nor necessarily wrong.

The newer question is what changes it. Interventions that reduce loneliness exist: group activities, befriending, social prescribing. The trials show an effect on the loneliness measure and none yet on death or hospital admission, because none has been large or long enough. Living alone is measured in every census and is rising in every ageing country. It is not the same thing as being lonely.

Trackers

At a glance

Updated
Evidence
—
Countries
—

Related drivers

Others we follow in Behavioural science.