COIOS
Healthcare today Item confirms peer-reviewed

A nutrition-inflammation index tracked short-term mortality in ICU kidney injury

In 1,887 critically ill adults with acute kidney injury in the MIMIC-IV database, a higher advanced lung cancer inflammation index was associated with lower in-hospital mortality (HR 0.86 per log unit) and lower 90-day mortality (HR 0.81), mainly in non-septic cases.

A retrospective cohort from the MIMIC-IV intensive care database examined the advanced lung cancer inflammation index, body mass index times serum albumin divided by the neutrophil-to-lymphocyte ratio, in 1,887 adults with acute kidney injury. In-hospital mortality was 25.2% and 90-day mortality 33.9%, and each log unit of the index carried an in-hospital mortality hazard ratio of 0.86 (95% CI 0.79-0.93) after full adjustment. The association weakened substantially on adjustment and was largely confined to non-septic cases, without external validation.

Why it is interesting: A further composite inflammation-nutrition index tested as an ICU prognostic marker in a single database.

Source
Clinics, 19 September 2026
DOI
10.1016/j.clinsp.2026.101156
Type
Peer-reviewed article
Design
Retrospective single-centre cohort using MIMIC-IV, 1,887 adult ICU patients with acute kidney injury
Verdict
Confirms prior evidence
Driver
Cancer