A prospective, double-blinded, non-randomised multicentre study compared compression ultrasounds of the proximal lower limb acquired by non-ultrasound-trained operators using an AI guidance system (ThinkSono Guidance) with standard-of-care ultrasound in 594 analysed patients, covering 700 scans and 67 proximal DVTs. Clinician-reviewed AI-guided scans were of diagnostic quality in 86.8% of cases, with triage sensitivity 92.9%, triage specificity 39.1% and prioritisation specificity 98.0%. Median combined scan and review time was 7.57 minutes, and standard-of-care ultrasound was reported as avoidable in 35.3% of patients.
Why it is interesting: The AI guidance changes who can perform the ultrasound rather than who reads it, with accuracy reported against a concurrent reference standard.