COIOS
Healthcare today Item confirms peer-reviewed

Cardiogenic shock deaths fall stepwise with hospital cardiac capability in US data

Across an estimated 1.18 million US cardiogenic shock hospitalisations from 2016 to 2022, crude in-hospital mortality fell from 64.4% at hospitals without percutaneous coronary intervention to 36.5% at transplant and LVAD centres, with the gradient persisting after adjustment.

Using the National Inpatient Sample for 2016-2022, hospitals were graded into five tiers of cardiac capability and in-hospital mortality after cardiogenic shock was modelled with a latent construct for acute physiological severity (cardiac arrest, acute kidney and liver injury, ventilation). Crude mortality declined from 64.4% at non-PCI hospitals to 36.5% at transplant/LVAD centres, and adjusted odds of death were roughly a third of tier 1 at higher tiers (tier 4 OR 0.34, 95% CI 0.30-0.38). Transfer-in status carried higher mortality (OR 1.36) but the penalty was attenuated at surgical and transplant centres.

Why it is interesting: Puts a size on the institutional gradient in cardiogenic shock survival, though administrative data cannot separate capability from case selection and transfer decisions.

Source
Circulation. Heart failure, 2026-09-15
DOI
10.1161/circheartfailure.126.014546
Type
Peer-reviewed article
Design
Retrospective analysis of US National Inpatient Sample, 2016-2022, ~1,177,180 cardiogenic shock hospitalisations, hospitals in five capability tiers, structural equation model with latent severity construct
Verdict
Confirms prior evidence
Driver
Cardiovascular disease