COIOS
Weighing data and models Item confirms preprint

Swiss children with obesity from poorer areas arrive with worse cardiometabolic risk

Among 886 children and adolescents at a Bern weight-management service, a 10-unit higher neighbourhood socioeconomic score was associated with a 2.57-point lower %BMIp95 and lower odds of insulin resistance, while treatment response did not differ by socioeconomic position.

The Bern Obesity in Childhood and Adolescence Biorepository linked a Swiss neighbourhood index of socioeconomic position to obesity severity and cardiometabolic markers in 886 children and adolescents (mean age 11.2 years) presenting to one specialised centre. A 10-unit higher socioeconomic score was associated with a 2.57-point lower %BMIp95 and lower odds of insulin resistance (OR 0.80), low HDL, elevated non-HDL and elevated triglycerides, partly mediated by reported physical activity and screen time. Among 419 with follow-up, the annual reduction in %BMIp95 and waist-to-height ratio did not differ by socioeconomic position.

Why it is interesting: The socioeconomic gradient appears at presentation, while the annual reduction did not differ by socioeconomic position in the 419 with follow-up.

Source
medRxiv, 27 September 2026
DOI
10.64898/2026.09.24.26362616
Type
Preprint
Design
Single-centre Swiss paediatric obesity biorepository, cross-sectional (n=886) with longitudinal follow-up (n=419)
Verdict
Confirms prior evidence
Driver
Revisions and new sources
Driver
Obesity, diabetes and GLP-1
Driver
Health funding and inequalities