COIOSDeep risk insights through multi-disciplinary research across the globe
brown concrete building
Item refines Peer-reviewed Added

Temperature-related mortality across 3,116 Dutch districts is dominated by cold, not heat

Cold was associated with 11,988 excess deaths a year in the Netherlands, heat with 346.

Daily temperature and all-cause mortality were analysed for 1,444,448 deaths in the Netherlands, 2010-2019. Case time series models estimated effects over the 21 days after exposure across 355 municipalities, then were downscaled to 3,116 districts. Heat was associated with 346 excess deaths yearly (44-558), cold with 11,988 (7,554-15,609). Standardised rates were 2.2 and 73.3 per 100,000 person-years; at 75+, relative risks were 1.05 and 1.18. Heat-related rates were highest in urban districts, cold-related rates in northern, south-western and south-eastern districts. District baseline risk was assumed uniform within municipalities, and spline knot placement left the heat estimates uncertain.

Why it is interesting: Cold is associated with far more excess deaths than heat in a temperate country. The two burdens fall in different parts of the country.

Source
Environmental Epidemiology, 17 October 2026
Paper
District-level analysis of temperature-related excess mortality in the Netherlands
Authors
Ndiaye A, Daanen H, van de Kassteele J, de Hoogh K, Zwakhals L, van Asten L et al.
DOI
10.1097/EE9.0000000000000534
Full text
Open copy (open-access copy, PubMed Central)
Type
Peer-reviewed article
Design
Three-stage small-area attribution: case time series with distributed lag nonlinear models across 355 municipalities, multivariate meta-regression pooling, downscaled to 3,116 districts, two age groups, 2010-2019
Verdict
Refines prior evidence
Driver
A changing climate
Abstract — the authors' own words, CC BY

Background:

While most epidemiological studies have assessed temperature–mortality associations at broad geographical scales, recent research highlights that temperature-related mortality risks are spatially heterogeneous due to local differences in exposure, vulnerability, and adaptive capacity. The aim of this study was to assess the impact of ambient air temperature on all-cause mortality at the district level in the Netherlands.

Methods:

A three-stage design was applied to assess the association between daily average air temperature and mortality across 3,116 districts and two age groups (0–74, 75+) for the period 2010–2019. First, a case time series design with distributed lag nonlinear models was used to estimate temperature–mortality associations for 355 Dutch municipalities. Second, municipality-level estimates were pooled using a multivariate meta-regression with municipality-level demographic, socioeconomic, climatological, and topographical predictors. Finally, the meta-regression model was used to downscale the risk estimates to the district level and to estimate standardized excess heat- and cold-related mortality rates.

Results:

Heat-related excess mortality was elevated in urban areas, whereas cold-related excess mortality was more pronounced in northern and southern districts compared with areas in the center of the Netherlands. During the study period, heat was associated with an average of 346 excess deaths per year (empirical 95% confidence intervals: 44–558), and cold with 11,988 excess deaths per year (7,554–15,609). This corresponds to standardized excess mortality rates of 2.2 (0.3–3.5) and 73.3 (46.8–94.7) per 100,000 person-years for heat and cold, respectively. The 75+ group showed more pronounced mortality risks compared with the younger age group.

Conclusion:

Our results indicate geographical heterogeneity in temperature-related standardized mortality rates, with high heat-related mortality in urban areas and more pronounced regional clustering of cold-related mortality. These findings can help local governments to implement climate adaptation measures to prevent heat- and cold-related excess mortality according to location-specific vulnerabilities.

Other drivers in Tomorrow's world