COIOS
Healthcare today Item refines peer-reviewed

Unemployed and unmarried Danes start cardioprotective diabetes drugs less often

Among 81,361 Danes with newly diagnosed type 2 diabetes and cardiovascular disease, initiation of SGLT2 inhibitors and GLP-1 receptor agonists was 23% lower in unemployed men and 19% lower in unemployed women than in the employed, while the educational gradient vanished after adjustment.

Danish health registries were used to follow 81,361 people with newly diagnosed concurrent type 2 diabetes and cardiovascular disease from 2015 to 2022, measuring initiation of SGLT2 inhibitors and GLP-1 receptor agonists. The crude gradient by education disappeared after multivariable adjustment (IRR 0.95 for women, 1.00 for men), but occupational and marital status did not - unemployed men had an IRR of 0.77 and unemployed women 0.81 against the employed, with retired, divorced, widowed and unmarried individuals also initiating less. Non-initiation was therefore patterned by work and partnership rather than by schooling.

Why it is interesting: In a system with universal coverage, the differential in who starts guideline-recommended cardioprotective drugs tracks employment and marital status rather than education.

Source
Diabetes, Obesity and Metabolism, 20 September 2026
DOI
10.1111/dom.71334
Type
Peer-reviewed article
Design
Danish nationwide registry cohort, 81,361 adults with new concurrent type 2 diabetes and cardiovascular disease, 2015-2022
Verdict
Refines prior evidence
Driver
Obesity, diabetes and GLP-1
Driver
Health funding and inequalities