Where the evidence stands
The phrase came from the United States, where deaths from drug overdose, alcohol and suicide rose steeply enough among middle-aged white adults from the late 1990s to reverse the country's mortality improvement — a pattern without parallel in other high-income countries. That much is established. What is mixed is nearly everything else. American overdose deaths peaked around 2023 and have since fallen sharply, for reasons that are argued over: fentanyl supply, naloxone, treatment, or the depletion of the population most at risk. Scotland has drug-death rates several times England's and the highest in Europe; alcohol deaths rose across the United Kingdom during and after the pandemic; suicide trends are flat or falling in most countries and rising in a few. The causal story — economic decline, loss of work, social fragmentation — that gave the phenomenon its name has held up less well than the descriptive one: the deaths are real and geographically specific, but their link to despair as such is weaker than the label implies. Policy evidence is stronger here than in most behavioural fields: minimum unit pricing in Scotland reduced alcohol deaths in a measurable way.
At a glance
- Status
- established
- Direction
- mixed
- Last changed
- Evidence
- —
- Countries
- —
Related drivers
Others we follow in Behavioural science.