The ARS-PARTICLES cohort followed 20 757 adults with atrial fibrillation in north-eastern Poland for a median 5.6 years. Annual ozone, nitrogen dioxide and PM2.5 were modelled and assigned by residential municipality from the previous year. Fine-Gray models accounted for competing deaths and adjusted for comorbidities, temperature, area-level income, light at night and co-pollutants. Each interquartile ozone increase (4.03 ug/m3) was associated with a composite of ischaemic stroke, TIA or stroke death. Subdistribution hazard ratios were 1.27 (95% CI 1.02-1.59) for the composite, 1.14 for cardiovascular mortality and 1.38 for stroke. Exposure was assigned by municipality from the address at entry, and anticoagulation and smoking data were unavailable.
Why it is interesting: Ozone is less studied than particulates, and here it is associated with stroke risk at low annual concentrations. The cohort is a high-risk clinical group rather than the general population.
Cite this item
BibTeX
Free sign-up. A digest of the new papers twice a week, grouped by domain.
Other drivers in Data, models and systems
-
Forecasts and their record
How the forecasts are made, how well they explained the past, and how well mortality can be forecast — and by whom.
5 this week -
What linked data reveals
What linked registries make it possible to know about whole populations
9 this week -
AI in medicine
Whether machine learning predicts, detects and decides better than the tools we have, and whether that has yet changed an outcome for a population.
5 this week -
Health systems and access
What the health system can provide, who gets it, and whether the gaps in health between groups are widening.
4 this week -
Value in health
What a treatment, health programme or policy is worth against what it costs, and how far the models that decide it can be trusted.
7 this week -
Revisions and new sources
What the figures are built from, what is newly available, and how much the numbers move when they are revised.
7 this week
