COIOSDeep risk insights through multi-disciplinary research across the globe
Woman wearing vr headset playing game on couch
Item refines Preprint · not peer-reviewed Added

Digital interventions for low back pain compared across 84 randomised trials

Virtual reality cut pain intensity most against control at the end of treatment, rated with moderate confidence.

This systematic review and network meta-analysis compared digital health interventions for adults with low back pain. It pooled 84 randomised trials with 11 649 participants from database and trial registry searches to August 2026. Formats included telemedicine, web and mobile apps, virtual reality, exergaming, biofeedback, face-to-face care and control. At the end of treatment, virtual reality reduced pain intensity most (SMD -1.43, 95% CI -1.87 to -0.98; moderate confidence). It was also linked to lower fear avoidance (SMD -1.14) and better quality of life (SMD 0.97). Its effect on physical function (SMD -0.86) and other estimates, such as self-efficacy, had very low confidence.

Why it is interesting: Digital care for back pain spans many formats, from telemedicine to virtual reality. This network meta-analysis compares seven formats against control in one analysis, with virtual reality ahead at the end of treatment.

Source
medRxiv, 2 November 2026
Paper
Comparative effectiveness of digital health interventions for low back pain: systematic review and network meta-analysis of randomised controlled trials
Authors
Chen R, Wu Z, Wei X, Yang W, Yan C, Chen H et al.
DOI
10.64898/2026.09.23.26363780
Type
Preprint
Design
Systematic review and frequentist random-effects network meta-analysis of 84 randomised trials (92 reports, 11,649 adults), databases from inception to August 2026
Verdict
Refines prior evidence
Driver
Medicine at a distance

Other drivers in Tomorrow's world