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Health todayHeart and stroke refines
Swings in blood pressure between visits carry higher abdominal aortic aneurysm risk
Among 189,770 UK Biobank participants, those with the most variable systolic readings had 33% to 54% higher risk of abdominal aortic aneurysm than those with the steadiest readings.
Peer-reviewed -
Tomorrow's worldMedicine at a distance refines
Exercise-based telerehabilitation raised peak oxygen uptake in cardiac patients
Telerehabilitation with exercise at its core raised peak oxygen uptake by 2.58 mL/kg/min in 13 randomised trials of 958 adults with cardiovascular disease, although the prediction interval crossed zero.
Peer-reviewed -
Health todayDementia refines
Only the intelligence part of an education genetic score tracks Alzheimer's
Across four cohorts of 3,483 participants, the intelligence-linked part of an education genetic score was inversely associated with Alzheimer's diagnosis, while the behavioural part was not.
Peer-reviewed -
Health todayHeart and stroke confirms
SGLT2 inhibitors show no new safety signals in diabetic kidney disease
In two US claims cohorts with type 2 diabetes and stage III to IV kidney disease, SGLT2 inhibitors showed only the known genital infection signal against GLP-1 receptor agonists.
Peer-reviewed -
Health todayCancer new
Projected cancer cases in sexual and gender minorities rise with self-identification
A projection applying cancer incidence rates to survey identification proportions estimated 15 times more cases at ages 55 to 59 among Millennial than Silent Generation sexual and gender minority Americans, 77,521 against 5,134 over five years, driven by who identifies rather than by risk.
Peer-reviewed -
Health todayDementia new
Varenicline users had about half the dementia rate of nicotine-replacement users
Among 1,758 matched pairs aged 50 and over in the All of Us cohort, varenicline users had about half the rate of dementia of those using nicotine replacement (HR 0.52).
Preprint · not peer-reviewed -
Health todayObesity, diabetes and GLP-1 new
Consistent glucose monitor users stayed on GLP-1 drugs longer in type 2 diabetes
In US claims for adults with type 2 diabetes starting a GLP-1 drug, 68.4% of consistent glucose monitor users were still on it at one year, against 51.9% of non-users.
Peer-reviewed -
Health todayCancer confirms
Parents of children with cancer report debt and long-term loss of household security
A review of 14 qualitative studies covering 524 participants in seven countries found medical costs, lost earnings and weak insurance left families in debt, with help giving only partial relief.
Peer-reviewed -
Health todayCancer confirms
Lower nutrition-inflammation score went with higher mortality in ICU kidney injury
In 1,887 intensive care patients with acute kidney injury, a higher nutrition and inflammation score was associated with lower in-hospital mortality, at a hazard ratio of 0.86 per log unit.
Peer-reviewed -
Data, models and systemsRevisions and new sources new
Amish study of 3,978 adults links cognitive diagnoses to pedigrees and whole-genome data
The Collaborative Amish Aging and Memory Project has enrolled 3,978 Amish adults in Ohio and Indiana, 2,928 with an agreed cognitive diagnosis, and reports only the cohort's composition.
Preprint · not peer-reviewed -
Health todayDementia confirms
Glial injury marker GFAP separates Alzheimer's stages more sharply than vascular markers
Among 2650 ADNI participants, the glial injury marker GFAP was 56.3% higher in Alzheimer's dementia than in unimpaired people, whereas vascular markers differed by around 14% and discriminated poorly.
Peer-reviewed -
Health todayHeart and stroke new
Spleen uptake on cardiac PET stress scans is associated with later cardiac events
Among 16,650 patients having drug-stress cardiac PET at six sites, a high ratio of spleen uptake under stress to uptake at rest was associated with more major cardiovascular events.
Peer-reviewed
