Healthcare today
Healthcare across the world faces existential challenges: escalating demands against constrained resources, increasing co-morbidities and widening inequalities in health.
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Healthcare today posts, most recent first.
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Item confirms Peer-reviewed
India's wealth gap in adult mortality has barely narrowed across two decades
Across three National Family Health Survey rounds from 1998–1999 to 2019–2021, adult mortality risk at ages 15–59 in India remained about 60% lower for men and 40% lower for women in the richest households than the poorest, with caste differentials only marginally reduced.
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Item contradicts Peer-reviewed
Reanalysed mammography trials are compatible with overdiagnosis below 5%
A reanalysis of randomised mammography trials, benchmarked against Denmark's Funen screening programme and adjusting for exit screening and follow-up timing, found excess-incidence patterns compatible with breast cancer overdiagnosis below 5%, against published estimates of up to 50%.
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Item new Preprint · not peer-reviewed
Mortality from secondary lung cancer rose 17.5% above 2000 levels in the US by 2024
Secondary malignant neoplasm of the lung (C78.0) recorded on death certificates rose from 7.22 per 100,000 population in 2008 to 11.38 in 2024, 17.5% above 2000 levels, with disproportionate increases among adults aged 25–34 years (70.5%).
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Item refines Peer-reviewed
Healthy working life expectancy at 50 averaged 11 years across 28 countries
In a 28-country cohort of 175,318 adults aged 50 and over, healthy working life expectancy at 50 was 10.98 years, 9.82 for women and 12.36 for men, with stroke associated with a 5.49-year reduction and higher health spending, governance quality and flexible work arrangements with longer spans.
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Item confirms Peer-reviewed
Home-based care use varies across Japan's municipalities despite universal insurance
Home-based long-term care services in Japan show significant geographic clustering and variation despite universal insurance coverage, associated with municipal characteristics including financial strength and care provider availability.
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Item refines Peer-reviewed
Polygenic score for osteoporosis shows modest discrimination gain in Japanese adults
A Japanese-ancestry polygenic score for ultrasound-defined osteoporosis added little to discrimination beyond age and sex, but quintile stratification gave incidence rate ratios of 1.42 in the lowest and 0.70 in the highest quintile over a mean 3.5 years of follow-up.
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Item refines Peer-reviewed
Weight loss drives bone loss through endocrine, nutritional and mechanical mechanisms
Weight loss raises bone turnover and lowers bone mineral density via endocrine, nutritional, mechanical and microbiota-mediated pathways, with greater loss in older and lean adults and after severe caloric restriction such as with GLP-1 drugs or bariatric surgery.
