-
Behavioural scienceDiet, exercise and sleep confirms
Moderate-to-vigorous activity and cardiovascular mortality in US adults with MASLD
Among 2785 adults with MASLD, 10 more minutes of moderate-to-vigorous activity gave a hazard ratio of 0.72 for cardiovascular death.
Peer-reviewed -
Data, models and systemsWhat linked data reveals refines
Social needs Z59 codes and subsequent acute care across 21 US health systems
Emergency visits were 67% higher after a first Z59 hardship code, but an administrative code reproduced much of this.
Preprint · not peer-reviewed -
Health todayObesity, diabetes and GLP-1 new
Type 2 diabetes remission is uncommon, brief and usually ended by a treatment restart
Recorded remission reached 3.82% at five years in treated adults, and ended more often by treatment restart than rising HbA1c.
Preprint · not peer-reviewed -
Data, models and systemsForecasts and their record refines
Parkinson's disease mortality in the US was flat from 1999 to 2025
Age-adjusted Parkinson's mortality was flat across 1999-2025; the post-2021 fall largely reflects the unwinding of COVID-19 co-listing.
Peer-reviewed -
Tomorrow's worldA changing climate contradicts
Wildfire smoke PM2.5 in US counties: excess deaths peak three years after exposure
Monthly county-level wildfire PM2.5 and mortality data gave 1.7 million smoke-associated deaths over 2011-2023, about ten times conventional estimates.
Preprint · not peer-reviewed -
Tomorrow's worldChanging behaviour at scale refines
Since 2021, low vaccine coverage predicts larger measles outbreaks in US counties
Since 2021, US counties with lower vaccine coverage have had larger measles outbreaks, and spread to neighbouring counties has increased.
Preprint · not peer-reviewed -
Data, models and systemsHealth systems and access confirms
Cervical cancer screening rises but gaps persist in US medical records, 2019-2024
Screening rates rose in all racial and ethnic groups from 2019 to 2024, with the largest gain among Hispanic patients.
Peer-reviewed -
Data, models and systemsWhat linked data reveals refines
CYP2D6 phenotype predicts metoprolol heart-rate response but not discontinuation
Reduced CYP2D6 activity lowered attained heart rate and raised bradycardia, but phenotype was not associated with stopping metoprolol.
Peer-reviewed -
Behavioural scienceSmoking and vaping refines
Digital outreach on lung screening eligibility reached 11% of invitees in North Carolina
Of 26,909 adults invited by patient portal or text, 11% completed lung screening eligibility questions within 16 weeks, with lower reach among Black and Hispanic patients.
Peer-reviewed -
Tomorrow's worldInnovation in treatment new
BCG immunotherapy lowers HbA1c for up to eight years in long-standing type 1 diabetes
HbA1c fell 7.04% from baseline at year 5 and 12.84% at year 8 with BCG, unchanged on placebo.
Preprint · not peer-reviewed -
Health todayObesity, diabetes and GLP-1 refines
Adding nutrition therapy to tirzepatide tracked with 19.7% weight loss against 15.6%
In a telemedicine obesity programme of 4,269 adults, GLP-1-naive tirzepatide users given individualised carbohydrate-reduced nutrition therapy lost 19.7% of body weight at 12 months, as compared to 15.6% without it.
Preprint · not peer-reviewed -
Data, models and systemsAI in medicine refines
Mortality models after intracerebral haemorrhage add little to the Glasgow Coma Scale
Models using the first 24 hours of ICU data after intracerebral haemorrhage reached external AUROCs of 0.80 to 0.85, against 0.78 to 0.81 for the Glasgow Coma Scale alone.
Preprint · not peer-reviewed
