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Data, models and systemsForecasts and their record new
21-valent pneumococcal vaccine could prevent 1.5-1.7 times as many cases as 20-valent
National surveillance and a multicentre pneumonia study in Japan estimate the 21-valent pneumococcal vaccine could prevent 1.5-1.7 times as many cases as the 20-valent in adults aged 65 and over.
Preprint · not peer-reviewed -
Data, models and systemsHealth systems and access confirms
Education and wealth are associated with lower biological age in 12 European countries
In 10,043 to 14,015 SHARE adults aged 50-75, every measure of socioeconomic advantage was associated with a lower estimated biological age, though the gap differed between the 12 countries.
Preprint · not peer-reviewed -
Data, models and systemsAI in medicine new
Model using intake records predicted six-month deaths in Taiwanese care homes
A model built from routine intake assessments in 636 Taiwanese care homes predicted death within 180 days of admission, with an AUROC of 0.90 in a separate 2024 cohort.
Peer-reviewed -
Data, models and systemsForecasts and their record new
New Zealand had few excess deaths through the pandemic and its aftermath
A model fitted to 22 years of monthly death counts estimates that New Zealand had few excess deaths during the pandemic, and was back to pre-pandemic mortality by 2025.
Peer-reviewed -
Health todayHeart and stroke new
The largest treatment gaps are not where cardiovascular risk could fall most
The populations with the largest treatment gaps were not those where treating currently untreated people would achieve the greatest absolute reduction in cardiovascular risk.
Peer-reviewed -
Health todayObesity, diabetes and GLP-1 refines
Diabetes was more common in older US influenza deaths than in COVID-19 deaths
Among US inpatients aged over 65 who died, 46.6% of those dying of COVID-19 had diabetes, as compared to 63.1% of those dying of influenza.
Peer-reviewed -
Data, models and systemsAI in medicine new
Language model identifies neurodegenerative disease from autopsy text in 75% of cases
In 5,613 Mayo Clinic autopsies, a language model scoring gross brain descriptions gave the correct diagnosis in 75% of held-out cases, but rarely identified combined Alzheimer and Lewy body disease.
Preprint · not peer-reviewed -
Data, models and systemsAI in medicine new
A locally run AI system removed 99.8% of identifiers planted in patient records
Of identifiers planted in 250 MIMIC-IV records extended with scans, handwriting and audio, 99.82% were removed, with every identifier removed for 98.80% of patients.
Preprint · not peer-reviewed -
Health todayCancer confirms
Modelled estimates put 10.6m new cancers at 65+ in 2022, rising 75% by 2036
A secondary analysis of GLOBOCAN 2022 and GBD 2021 estimates reports 10.6 million new cancer cases and 6.0 million cancer deaths among adults aged 65 and over in 2022, with the modelled case count projected to rise 75.5% by 2036 as populations age.
Peer-reviewed -
Health todayHeart and stroke confirms
Asian Pacific Islanders had worse in-hospital outcomes after heart attack in the US
A propensity-matched analysis of US hospital admissions for heart attack from 2003 to 2022 found higher in-hospital mortality among Asian Pacific Islander patients than among other patients.
Peer-reviewed -
Health todayCancer contradicts
Reanalysed mammography trials are compatible with breast cancer overdiagnosis below 5%
A reanalysis of randomised mammography trials, benchmarked against Denmark's Funen screening programme, found the extra cancers detected compatible with breast cancer overdiagnosis below 5%, against published estimates up to 50%.
Peer-reviewed -
Data, models and systemsWhat linked data reveals refines
Austrian registry data show vaccinated adults died less from causes vaccines cannot affect
In Austrian adults with no documented prior infection, vaccinated people had lower mortality from cancer and external causes, with adjusted all-cause hazard ratios of 0.24 to 0.32 in the two weeks after a dose, a measure of the healthy vaccinee effect.
Preprint · not peer-reviewed
