This meta-analysis pooled individual data from 22 longitudinal community-based cohorts, 38,418 people in 18 countries or territories. Over 287,632 person-years at risk, 3001 participants developed dementia, giving a standardised incidence of 9.7 per 1000. Incidence was higher in women than men, 10.6 against 8.6 per 1000 person-years. It was higher in low- and middle-income countries, 13.6 against 8.3 in high-income countries. Applying the rates to the 2050 projected population gave 24.7 million new cases, assuming constant incidence. Baseline recruitment took place between 1990 and 2011, so the rates predate recent changes.
Why it is interesting: It reports harmonised incidence rates rather than prevalence, separating new cases from survival. The excess in low- and middle-income countries and the constant-incidence projection both affect the global count.
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