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Item refines Preprint · not peer-reviewed Added

Health opportunity cost estimates updated for 92 low- and middle-income countries

The marginal cost per DALY averted ranges from about $54 to $18,547 across 92 low- and middle-income countries.

The study re-estimates the marginal cost per DALY averted from government health expenditure in 92 low- and middle-income countries. Elasticities from Ochalek et al. (2018) were applied to recent mortality, morbidity, population and expenditure data, not re-estimated. Estimates ranged from about $54 to $18,547 per DALY averted, higher than Ochalek et al. (2018) in 68% of countries. Raising government health spending to a tiered minimum of 10% or 15% would avert 145 million DALYs, costing $392 billion. Reallocating $11.2 billion of on-budget development assistance by country-specific opportunity cost would avert 75.3 million DALYs, against 45.3 million now. Allocating the $25.7 billion off-budget, NGO and philanthropic envelope would avert 66.1 million more, from a baseline of none.

Why it is interesting: Earlier versions of these estimates informed priority setting in several countries and international policy discussions. The reallocation scenarios put a figure on what current donor allocation may forgo.

Source
medRxiv, 15 October 2026
Paper
Updated Health Opportunity Cost Estimates for 92 Low- and Middle-Income Countries: Implications for Global Health Financing and Donor Allocation
Authors
Ochalek JM
DOI
10.64898/2026.03.31.26349880
Type
Preprint
Design
Economic modelling study applying previously estimated expenditure–outcome elasticities (Ochalek et al. 2018) to recent mortality, morbidity, population and government health expenditure data for 92 low- and middle-income countries, with two allocation scenarios
Verdict
Refines prior evidence
Driver
Health systems and access
Driver
Revisions and new sources
Driver
Value in health

Other drivers in Data, models and systems