COIOS
Tomorrow's world Item refines peer-reviewed

Korea's 2025-26 avian flu season carried diverse H5Nx genotypes, one of European origin

Genomic surveillance of 62 poultry outbreaks and 63 wild bird detections in Korea during winter 2025-26 found extensive clade 2.3.4.4b reassortment, including the European H5N1 genotype EA-2024-DI.2.1 that spread across Europe in 2025, alongside novel H5N1 and H5N9 poultry genotypes.

Researchers sequenced clade 2.3.4.4b H5N1, H5N6 and H5N9 viruses from 62 poultry outbreaks and 63 wild bird cases in Korea over winter 2025-26, and tested two isolates in chickens and ducks. Most genotypes were reassortants of East Asian H5N1 with low-pathogenicity wild bird viruses, and the European genotype EA-2024-DI.2.1 was also detected. H5N1 and H5N9 were highly infective in chickens (median lethal doses of 10^3.3 and 10^3.2 EID50); in young ducks H5N1 killed rapidly while H5N9 caused no mortality but still transmitted to all contact birds.

Why it is interesting: A European H5N1 genotype reached East Asia within a season and reassorted locally, with H5N9 transmitting silently in ducks.

Source
Virus Research, 22 September 2026
DOI
10.1016/j.virusres.2026.199807
Type
Peer-reviewed article
Design
Whole-genome surveillance of clade 2.3.4.4b H5Nx from 62 poultry outbreaks and 63 wild bird cases, Korea, winter 2025-26, with chicken and duck pathogenicity experiments
Verdict
Refines prior evidence
Driver
Infection and pandemics