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Tomorrow's worldMedicine at a distance refines
Systolic pressure was 5.8 mmHg lower with apps and wearables after stroke
Across 29 studies in 8,389 stroke and transient ischaemic attack survivors, systolic blood pressure was 5.8 mmHg lower with mobile applications or wearables, though prediction intervals crossed the null.
Peer-reviewed -
Behavioural scienceAdherence and persistence refines
Tirzepatide initiators stayed on treatment longer than semaglutide initiators
In propensity-matched US claims data on adults with type 2 diabetes, 12-month adherence was 60% for tirzepatide initiators against 45% for semaglutide initiators among GLP-1-naive patients, with persistence of 62% against 47%.
Peer-reviewed -
Tomorrow's worldSlowing ageing itself refines
Proteomic organ clocks tracked 16-year mortality less closely than epigenetic age
Accelerated liver, immune and heart proteomic ageing carried hazard ratios of 1.38 to 1.43 per standard deviation for 16-year mortality, below those for epigenetic age and cognition.
Peer-reviewed -
Health todayObesity, diabetes and GLP-1 new
GLP-1 prescribing to US children aged 8-11 with obesity rose but stayed under 1%
Among 3.5 million US children aged 8 to 11 with obesity and without diabetes recorded in Epic Cosmos between 2019 and June 2026, 0.6% received a GLP-1 receptor agonist prescription, with rates highest among 11-year-olds, girls, and those with obesity-related comorbidities.
Peer-reviewed -
Tomorrow's worldA changing climate new
Daily cancer deaths in Japan were 0.88% higher per 10 micrograms/m3 of PM2.5
A 10 microgram per cubic metre rise in PM2.5 was associated with 0.88% more cancer deaths in Japan, though the association did not survive adjustment for NO2 or SO2.
Peer-reviewed -
Data, models and systemsValue in health new
Modelled depression screening of KwaZulu-Natal sex workers averts HIV at $490 per QALY
A transmission model for KwaZulu-Natal found depression screening with behavioural treatment most cost-effective among female sex workers, at $350 per HIV infection averted and $490 per QALY gained.
Peer-reviewed -
Behavioural scienceAlcohol and drug use new
One in nine older US cannabis users meets criteria for cannabis use disorder
In a national US survey, 8.9% of adults aged 65 and over had used cannabis in the past year, and 11.4% of those met criteria for cannabis use disorder.
Peer-reviewed -
Health todayObesity, diabetes and GLP-1 new
Oral GLP-1 tablet safiglipron cut HbA1c by up to 1.45 points in type 2 diabetes
In the OUTSTAND-1 trial, once-daily safiglipron tablets lowered HbA1c by up to 1.45 percentage points more than placebo over 32 weeks in untreated type 2 diabetes.
Peer-reviewed -
Behavioural scienceSocial connection refines
Loneliness predicts psychological distress better than other social measures
In a 29-country European survey of 48,377 respondents, loneliness was the strongest social predictor of psychological distress, and the other social measures together added 0.006 to the AUC.
Peer-reviewed -
Health todayDementia refines
APOE e4 dementia risk is largest in European ancestry across 367,757 US adults
A study of APOE genotype against 2,632 traits and conditions in 367,757 All of Us participants found 27 associations, with dementia risk largest in those of European ancestry.
Preprint · not peer-reviewed -
Health todayHeart and stroke new
Between 15% and 49% of heart disease patients had clinically elevated cardiac anxiety
A review of 26 studies in 9,628 patients with cardiovascular disease found clinically elevated fear of cardiac sensations in 15% to 49%, varying with the questionnaire cut-off used.
Peer-reviewed -
Health todayObesity, diabetes and GLP-1 confirms
Lower education was the most consistent marker of obesity in Korean adults
Analysis of Korea's national health and nutrition survey for 2022 to 2024 found lower education the most consistent marker of obesity in adults, with income and employment less consistent.
Peer-reviewed
