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Item new peer-reviewed
Deprivation and renting track loneliness in excess of isolation among older English adults
In 8,164 English adults aged 60 and over followed across three ELSA waves, every socioeconomic indicator examined was independently associated with the gap between reported loneliness and measured social isolation, with renting and low internet use marking the largest vulnerability.
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Item confirms preprint
Vaccinated Spanish women show less HPV 16/18 and fewer high-grade cervical lesions
Among 908 women in Spanish cervical screening, HPV 16/18 was detected in 0.76% of vaccinated versus 5.5% of unvaccinated women, and high-grade cytological lesions in 0.38% versus 2.4%.
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Item refines preprint
Power to Quit campaign coincided with more quit attempts but no change in success
A pre/post evaluation of England's Power to Quit mass media campaign found quit attempts rose from 48.4% to 52.3% and use of digital support from 16.0% to 18.4%, both with confidence intervals spanning no effect, and no clear change in quit success.
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Item new preprint
PCV20 lowered pneumococcal pneumonia admissions by a fifth in US adults aged 65 and over
In 34,009 US Veterans Affairs pneumonia hospitalisations with respiratory cultures taken between 2023 and 2025, the 20-valent pneumococcal conjugate vaccine was associated with 20.4% lower odds of culture-confirmed pneumococcal pneumonia among adults aged 65 and over.
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Item confirms peer-reviewed
Advanced CKD tracks higher in-hospital death in STEMI shock on circulatory support
In 63,755 weighted US hospitalisations for STEMI with cardiogenic shock treated with mechanical circulatory support, in-hospital mortality rose from 30.7% with no chronic kidney disease to 40.7% with stage 4–5 disease, an adjusted odds ratio of 1.26.
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Item new peer-reviewed
No epidemiological evidence yet links e-cigarettes or snus to chemotherapy response
A systematic review of alternative tobacco and nicotine products during anticancer therapy found no epidemiological study of their effect on chemotherapy response, and a single in vitro signal of e-cigarette-induced cisplatin resistance failed to replicate in a multi-centre study.
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Item confirms peer-reviewed
Modelled estimates put 10.6m new cancers at 65+ in 2022, rising 75% by 2036
A secondary analysis of GLOBOCAN 2022 and GBD 2021 estimates reports 10.6 million new cancer cases and 6.0 million cancer deaths among adults aged 65 and over in 2022, with the modelled case count projected to rise 75.5% by 2036 as populations age.
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Item confirms peer-reviewed
Asian Pacific Islanders had higher in-hospital death after heart attack than others in US
A propensity-matched analysis of US National Inpatient Sample admissions for acute myocardial infarction between 2003 and 2022 reports higher in-hospital mortality and more cardiac arrest, cardiogenic shock and stroke among Asian Pacific Islander patients than among others.
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Item new peer-reviewed
Pharmacies gave 42% of first COVID vaccine doses to North Carolina children
Analysis of North Carolina's COVID-19 Vaccine Management System records for 1.75 million children aged 3-17 found pharmacies administered 42% of first doses, with an equal share in rural, suburban and urban areas but lower use among Black and Hispanic children.
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Item new peer-reviewed
GLP-1 users with obesity and asthma recorded fewer exacerbations than other weight drugs
In a propensity-matched TriNetX cohort of 4,846 adults with obesity and documented asthma, one-year recorded exacerbations were 1.7% with GLP-1-based therapy versus 4.0% with non-GLP weight-management drugs (risk ratio 0.44), with the authors ruling out causal inference.
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Item confirms peer-reviewed
India's wealth gap in adult mortality has barely narrowed across two decades
Across three National Family Health Survey rounds from 1998–1999 to 2019–2021, adult mortality risk at ages 15–59 in India remained about 60% lower for men and 40% lower for women in the richest households than the poorest, with caste differentials only marginally reduced.
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Item refines peer-reviewed
Heat exposure raises COPD mortality by 26% and morbidity by 5% across 36 studies
A meta-analysis of 36 observational studies found heat exposure associated with a pooled risk ratio of 1.15 for COPD outcomes overall, 1.26 for mortality and 1.05 for morbidity, with heatwave and threshold definitions giving larger estimates than continuous temperature measures.
