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Data, models and systemsAI in medicine confirms
Machine learning beat risk scores for predicting AF recurrence after catheter ablation
Across 11 studies, machine learning pooled a C-statistic of 0.80 for AF recurrence after ablation, against 0.58 for traditional scores.
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Health todayMental health contradicts
Life expectancy gap for hospitalised psychiatric illness narrowed in Queensland, 2009-2023
The life expectancy gap at age 18 narrowed in both sexes over 14 years, but not in schizophrenia.
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Health todayObesity, diabetes and GLP-1 new
Tirzepatide price rise shifted UK self-paying patients to semaglutide
Among 1,033,522 UK adults self-funding GLP-1 treatment, semaglutide initiation rose 31 percentage points in the month tirzepatide's list price rose.
Peer-reviewed -
Health todayDementia refines
Dementia incidence 9.7 per 1000 person-years, higher in low- and middle-income countries
Age- and sex-standardised all-cause dementia incidence was 9.7 per 1000 person-years across 22 cohorts in 18 countries.
Peer-reviewed -
Behavioural scienceAlcohol and drug use refines
Austrian opioid agonist treatment cohort has excess mortality across all major causes
Among 26,031 people in Austria's opioid agonist treatment registry, all-cause mortality was 7.06 times the general population rate in women and 3.86 times in men.
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Data, models and systemsWhat linked data reveals refines
CYP2D6 phenotype predicts metoprolol heart-rate response but not discontinuation
Reduced CYP2D6 activity lowered attained heart rate and raised bradycardia, but phenotype was not associated with stopping metoprolol.
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Data, models and systemsValue in health new
NHS online diabetes self-management service modelled at £13,192 per QALY
A patient-level simulation of an NHS online service for type 2 diabetes estimated a gain of 0.016 QALYs and a net cost of £216 per user.
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Health todayCancer new
Cancer in Japanese adults aged 85 and over rose more than four-fold between 1995 and 2020
Registry data show cancer cases in the oldest-old rising 5.9% a year, reaching 15.7% of all Japanese cases by 2020.
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Behavioural scienceSmoking and vaping refines
Digital outreach on lung screening eligibility reached 11% of invitees in North Carolina
Of 26,909 adults invited by patient portal or text, 11% completed lung screening eligibility questions within 16 weeks, with lower reach among Black and Hispanic patients.
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Behavioural scienceAlcohol and drug use new
Worklessness through ill health in England rose fastest among non-drinkers, 2014 to 2025
Health-related economic inactivity doubled among non-drinkers and low-risk drinkers, while falling among those drinking at levels indicating possible dependence.
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Behavioural scienceAdherence and persistence new
Dexamphetamine persists longer than methylphenidate over 12 months in adults with ADHD
Among adults starting stimulants for ADHD, median time to switching or stopping was 33.1 weeks for dexamphetamine and 15.0 weeks for methylphenidate.
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Health todayHeart and stroke refines
Tirzepatide versus dulaglutide in type 2 diabetes, by heart failure status
Tirzepatide gave a hazard ratio of 0.83 for all-cause death or heart failure events in those with prior heart failure.
Peer-reviewed
