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Behavioural scienceSocial connection refines
Friend isolation, not family isolation, is linked to mortality in disaster survivors
Among 9311 earthquake survivors followed 5.9 years, isolation from friends was associated with an adjusted hazard ratio for death of 1.28.
Peer-reviewed -
Behavioural scienceSocial connection refines
Social connection clusters and mortality in 2 265 older adults in Santiago, Chile
Clusters lacking a partner, social participation or perceived support had higher all-cause mortality among older Chileans without multimorbidity at baseline.
Peer-reviewed -
Tomorrow's worldInnovation in treatment new
BCG immunotherapy lowers HbA1c for up to eight years in long-standing type 1 diabetes
HbA1c fell 7.04% from baseline at year 5 and 12.84% at year 8 with BCG, unchanged on placebo.
Preprint · not peer-reviewed -
Data, models and systemsHealth systems and access new
Life expectancy in 28 countries modelled by machine learning on six drivers
Machine learning on a 28-country panel found a concave income-longevity link, and projected mean life expectancy of 78.21 years in 2032 under baseline against 78.98 under an integrated prevention scenario.
Peer-reviewed -
Health todayCancer refines
Three in five women aged 30-49 have never had cervical screening
Three in five women aged 30-49 worldwide have never been screened for cervical cancer, and 92% have never had an HPV test.
Peer-reviewed -
Health todayObesity, diabetes and GLP-1 refines
Adding nutrition therapy to tirzepatide tracked with 19.7% weight loss against 15.6%
In a telemedicine obesity programme of 4,269 adults, GLP-1-naive tirzepatide users given individualised carbohydrate-reduced nutrition therapy lost 19.7% of body weight at 12 months, as compared to 15.6% without it.
Preprint · not peer-reviewed -
Behavioural scienceInfection and pandemics confirms
Vaccinated adults had a quarter lower odds of long COVID in the Omicron era
An updated meta-analysis of 18 observational studies estimated the odds of long COVID at 0.75 in vaccinated adults against unvaccinated, and 0.63 for boosted against primary course only.
Preprint · not peer-reviewed -
Data, models and systemsAI in medicine refines
Mortality models after intracerebral haemorrhage add little to the Glasgow Coma Scale
Models using the first 24 hours of ICU data after intracerebral haemorrhage reached external AUROCs of 0.80 to 0.85, against 0.78 to 0.81 for the Glasgow Coma Scale alone.
Preprint · not peer-reviewed -
Data, models and systemsAI in medicine new
Automated coronary calcium scoring stratified risk better than expert reading
Tested in 5,969 patients, an automated coronary calcium model stratified risk of death or myocardial infarction better than experts reading the same low-dose CT scans.
Preprint · not peer-reviewed -
Tomorrow's worldA changing climate new
More days above the WHO daily NO2 guideline are followed by faster cognitive decline
Among 12,235 English adults aged 50 and over, more days above the WHO daily NO2 guideline were followed by faster decline in memory and fluency, independent of annual mean exposure.
Preprint · not peer-reviewed -
Health todayCancer refines
Cancer cachexia episodes coincide with disease progression and lower survival
In 52,236 patients with cancer, cachectic weight loss episodes occurred at times of disease progression, were linked to lower survival, and were more common in tumours with TP53 mutations.
Peer-reviewed -
Data, models and systemsRevisions and new sources new
Published rules for detecting statin intolerance agree poorly with Australian GP records
Statin intolerance was recorded in 5.09% of Australian primary-prevention statin users, and none of six published rules for detecting it from records matched a locally developed reference standard consistently.
Preprint · not peer-reviewed
