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Data, models and systemsWhat linked data reveals new
Swedish resource SIMPLER links 107,000 adults' diet data to national registers
The Swedish research infrastructure SIMPLER brings together two cohorts, 61,433 women recruited in 1987-90 and 45,906 men in 1997, with repeated diet questionnaires, register linkage and stored biological samples.
Peer-reviewed -
Health todayFrailty and multimorbidity new
Sixty of 99 dietary factors are associated with hip fracture in UK women
Among 541,887 UK postmenopausal women followed for about 20 years, 60 of 99 dietary factors were associated with hip fracture risk after correction for multiple testing.
Peer-reviewed -
Behavioural scienceAlcohol and drug use refines
Drug-poisoning deaths are set against the change in US life expectancy, 2019 to 2024
A cross-sectional study examines how far changes in drug-poisoning deaths account for the change in US life expectancy between 2019 and 2024.
Peer-reviewed -
Behavioural scienceInfection and pandemics new
Bangladesh's measles outbreak has killed up to 1144, most of them children
Bangladesh has recorded 22 116 laboratory-confirmed measles cases since mid-March and a death toll put as high as 1144, while officials say their own confirmed counts are an underestimate.
Agency -
Tomorrow's worldA changing climate refines
Wildfire smoke PM2.5 is associated with higher dementia incidence in older US adults
Each microgram per cubic metre of wildfire smoke PM2.5 was associated with a 2.9% increase in the incidence rate of dementia among 39.7 million US Medicare beneficiaries followed to 2019.
Preprint · not peer-reviewed -
Data, models and systemsHealth systems and access refines
US county excess deaths linked to education and insurance coverage
A screen of 2,745 county-level variables found the strongest correlates of US county excess deaths were college attainment (-0.54) and uninsurance at ages 40-64 (+0.53).
Preprint · not peer-reviewed -
Behavioural scienceDiet, exercise and sleep refines
Mid-life exercise of about an hour a day reduces hip fracture risk
In 324,284 UK Biobank adults followed for 16 years, hip fracture risk was lowest at about one hour a day of leisure-time activity, with no further reduction at higher volumes.
Preprint · not peer-reviewed -
Data, models and systemsHealth systems and access new
GP requests for specialist advice led to later diagnoses than referral alone
Among 71,145 patients in English primary care records, those whose GP sought specialist advice before referring were diagnosed later than those referred electively, by 15.9 weeks for inflammatory bowel disease.
Preprint · not peer-reviewed -
Health todayHeart and stroke new
Top 10% by polygenic risk carry a fifth of Taiwan's atrial fibrillation
Taiwan Biobank genotypes were linked to national insurance claims for 140,000 people, and those in the top 10% by polygenic risk were 3.56 times as likely to develop atrial fibrillation.
Preprint · not peer-reviewed -
Behavioural scienceInfection and pandemics new
Higher HPV antibody levels are associated with greater vaccine efficacy across types
A Bayesian meta-analysis of randomised HPV vaccine trials found higher type-specific antibody levels associated with greater efficacy against infection and CIN2+, with the level associated with protection differing by type.
Preprint · not peer-reviewed -
Tomorrow's worldSlowing ageing itself refines
Immune gene HLA-DRB1*04 is commoner in centenarians, DRB1*01:01 in Alzheimer's patients
Fine-mapping of HLA class II immune genes in 6,053 people found DRB1*04 subtypes commoner in 443 cognitively healthy centenarians, and DRB1*01:01 commoner in the 2,391 Alzheimer's patients.
Preprint · not peer-reviewed -
Health todayMental health refines
Severe mental illness costs Norwegian men 1.5 to 19.9 life-years depending on subgroup
In a Norwegian registry cohort of 2,486,836 adults followed from 2008 to 2023, excess life-years lost from age 30 in men ranged from 1.50 for depression with non-inpatient care and university education to 19.86 for schizophrenia with inpatient care and less than high school education.
Preprint · not peer-reviewed
