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Tomorrow's worldA changing climate refines
Temperature-related mortality across 3,116 Dutch districts is dominated by cold, not heat
Cold was associated with 11,988 excess deaths a year in the Netherlands, heat with 346.
Peer-reviewed -
Data, models and systemsForecasts and their record refines
Parkinson's disease mortality in the US was flat from 1999 to 2025
Age-adjusted Parkinson's mortality was flat across 1999-2025; the post-2021 fall largely reflects the unwinding of COVID-19 co-listing.
Peer-reviewed -
Tomorrow's worldA changing climate new
Drought-attributable excess mortality in Somalia, 2015-2024: a small-area modelling study
Modelling estimated 71,100 excess deaths in Somalia during the 2022-2024 drought, 91% of them children under 5.
Peer-reviewed -
Health todayCancer refines
Smaller colorectal tumours linked to nodal metastasis risk and worse survival in subgroups
In 10,513 colorectal cancer patients, smaller tumour diameter raised predicted lymph node metastasis risk and, below 3 cm, mortality.
Peer-reviewed -
Data, models and systemsWhat linked data reveals refines
Primary care death records match ONS registrations for 88% of deaths in OpenSAFELY-TPP
Of 1,409,275 ONS-registered deaths from 2020 to 2025, 88% had the same date of death in primary care and 8% had none.
Preprint · not peer-reviewed -
Tomorrow's worldA changing climate contradicts
Wildfire smoke PM2.5 in US counties: excess deaths peak three years after exposure
Monthly county-level wildfire PM2.5 and mortality data gave 1.7 million smoke-associated deaths over 2011-2023, about ten times conventional estimates.
Preprint · not peer-reviewed -
Data, models and systemsHealth systems and access refines
Health opportunity cost estimates updated for 92 low- and middle-income countries
The marginal cost per DALY averted ranges from about $54 to $18,547 across 92 low- and middle-income countries.
Preprint · not peer-reviewed -
Tomorrow's worldChanging behaviour at scale refines
Since 2021, low vaccine coverage predicts larger measles outbreaks in US counties
Since 2021, US counties with lower vaccine coverage have had larger measles outbreaks, and spread to neighbouring counties has increased.
Preprint · not peer-reviewed -
Health todayHeart and stroke refines
Type 2 diabetes being diagnosed at older ages in Israel, and with more co-morbidities
Median age at diagnosis rose from 63.0 to 66.7 years between 2005-2008 and 2020-2023 in one Israeli health system.
Peer-reviewed -
Tomorrow's worldSlowing ageing itself refines
Short telomeres, not epigenetic or proteomic ageing, raise interstitial lung disease risk
Of six ageing measures tested against six immune-mediated diseases, only longer leukocyte telomeres lowered interstitial lung disease risk.
Preprint · not peer-reviewed -
Tomorrow's worldInnovation in treatment new
VES001, an oral sortilin inhibitor, raised plasma and CSF progranulin in healthy adults
In a randomised placebo-controlled first-in-human trial, twice-daily oral VES001 for 7 days raised plasma progranulin by up to 49% and CSF progranulin by 18% from baseline.
Peer-reviewed -
Data, models and systemsHealth systems and access confirms
Cervical cancer screening rises but gaps persist in US medical records, 2019-2024
Screening rates rose in all racial and ethnic groups from 2019 to 2024, with the largest gain among Hispanic patients.
Peer-reviewed
