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Behavioural scienceSocial connection new
Carers who repeatedly stop and restart unpaid care are more likely to smoke
In the UK Household Longitudinal Study, adults repeatedly moving in and out of unpaid caring had higher odds of smoking (OR 1.67) and lower odds of physical inactivity (OR 0.65).
Preprint · not peer-reviewed -
Data, models and systemsAI in medicine refines
Polygenic scores add most to prediction where clinical risk is already low
Across 150 diseases in 900,000 UK Biobank and FinnGen participants, polygenic scores added most in metabolic, cardiovascular, autoimmune and neurological disease, and added little for genitourinary and respiratory conditions.
Preprint · not peer-reviewed -
Behavioural scienceAlcohol and drug use refines
Scottish drug deaths rose 11% in 2025, with nitazenes linked to a fifth of fatalities
Drug-related deaths in Scotland rose by 11% to 1133 in 2025, with 247 (22%) linked to nitazenes, more than triple the 2024 figure, although routine postmortem testing for etonitazene began only in May 2025.
Official statistics -
Data, models and systemsRevisions and new sources new
UK database lists the additives that mark a food as ultra-processed
Researchers have sorted every additive approved in the UK by its purpose, so that those used to alter taste, colour or texture mark a product as ultra-processed.
Preprint · not peer-reviewed -
Behavioural scienceDiet, exercise and sleep refines
Older adults walked 483 fewer steps after a day of higher fine particle exposure
In 67 UK adults aged 50-85, a day on which fine particle exposure ran 2.6 micrograms per cubic metre above the person's own average was followed by 483 fewer steps.
Preprint · not peer-reviewed -
Health todayCancer new
Blood-based multicancer screening did not reduce late-stage cancer in 142,250 adults
In the NHS-Galleri trial of 142,250 adults in England, three annual rounds of multicancer early-detection testing did not reduce stage III or IV cancer incidence (rate ratio 1.03).
Peer-reviewed -
Data, models and systemsWhat linked data reveals new
England's linked child health and school records miss deprived and minoritised children
ECHILD, which links hospital, school and social care records for 21 million children in England, includes children in deprived areas and in minoritised ethnic groups less often than others.
Preprint · not peer-reviewed -
Behavioural scienceDiet, exercise and sleep refines
The most active mid-life adults in UK Biobank report more fractures
Among 322,749 UK Biobank participants in mid-life, fracture in the previous five years was more common in the most active fifth, but not in those meeting WHO recommendations.
Preprint · not peer-reviewed -
Behavioural scienceInfection and pandemics new
Canada's missing measles vaccine coverage figures are filled in by modelling
Researchers curated publicly available Canadian vaccine coverage data and modelled first-dose measles coverage by province, territory and age, then tested the same method against England's more complete records.
Preprint · not peer-reviewed -
Behavioural scienceSocial connection confirms
Isolation's link with death was weaker in UK Biobank adults using mixed transport
Social isolation carried a hazard ratio of 1.34 for all-cause death in 490,114 UK Biobank adults, and the link was weaker in those using a car alongside other transport.
Preprint · not peer-reviewed -
Behavioural scienceSmoking and vaping refines
Smokers and e-cigarette users with a smoking history report more long-standing illness
In the 2022 Health Survey for England, those who both smoked and vaped had 2.35 times the adjusted odds of a long-standing condition as never users, and smokers 1.87 times.
Peer-reviewed -
Health todayCancer refines
Galleri blood test found 26.7% to 37.2% of cancers per screening round
In the NHS-Galleri trial of 142,250 adults aged 50 to 77, the multi-cancer blood test detected between 26.7% and 37.2% of cancers in each of three annual screening rounds.
Peer-reviewed
