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Health todayCancer new
Blood-based multicancer screening did not reduce late-stage cancer in 142,250 adults
In the NHS-Galleri trial of 142,250 adults in England, three annual rounds of multicancer early-detection testing did not reduce stage III or IV cancer incidence (rate ratio 1.03).
Peer-reviewed -
Data, models and systemsWhat linked data reveals new
England's linked child health and school records miss deprived and minoritised children
ECHILD, which links hospital, school and social care records for 21 million children in England, includes children in deprived areas and in minoritised ethnic groups less often than others.
Preprint · not peer-reviewed -
Behavioural scienceInfection and pandemics refines
Korea's 2025-26 avian flu outbreaks included an H5N1 genotype from Europe
Sequencing of H5Nx viruses from 62 poultry outbreaks and 63 wild bird cases in Korea found most H5N1 and H5N9 genotypes were reassortants, one of them a genotype from Europe.
Peer-reviewed -
Behavioural scienceAlcohol and drug use new
Australian MDMA-related poisoning deaths rose to 2019 and then fell to 2023
A coronial series of 217 MDMA-related fatal poisonings in Australia found the population rate rising to 2019 and falling to 2023, with other psychoactive drugs detected in 91.7% of cases.
Peer-reviewed -
Health todayObesity, diabetes and GLP-1 refines
Unemployed and unmarried Danes start cardioprotective diabetes drugs less often
Among 81,361 Danes with type 2 diabetes and cardiovascular disease, unemployed men started cardioprotective glucose-lowering drugs at 0.77 times the rate of employed men, and unemployed women 0.81 times.
Peer-reviewed -
Health todayObesity, diabetes and GLP-1 new
Photo review found compounded products in a quarter of surveyed US GLP-1 users
Blinded review of medication photographs classified 25.8% of 322 US adults on weekly semaglutide or tirzepatide as using compounded products, with self-report agreeing for 82.6%.
Peer-reviewed -
Health todayHeart and stroke refines
Door-to-balloon under 60 minutes linked to lower mortality only in higher-risk STEMI
Among 4,513 STEMI patients in China, a door-to-balloon time over 60 minutes carried 1.69x the three-year mortality in those at higher risk on admission, but no difference at lower risk.
Peer-reviewed -
Health todayFrailty and multimorbidity refines
Walking speed predicts survival at ages 90-94, but not beyond
Among 502 adults aged 90 and over, each 0.21 m/s of faster walking speed was associated with 20% lower mortality, although the association was absent beyond age 95.
Peer-reviewed -
Tomorrow's worldMedicine at a distance refines
Pacemakers after cardiac surgery carry higher later death and heart failure risk
Among 76 223 Swedish adults having cardiac surgery, the 2.8% given a pacemaker within 30 days had a higher adjusted risk of death and of heart failure admission over 6.8 years.
Peer-reviewed -
Behavioural scienceDiet, exercise and sleep refines
The most active mid-life adults in UK Biobank report more fractures
Among 322,749 UK Biobank participants in mid-life, fracture in the previous five years was more common in the most active fifth, but not in those meeting WHO recommendations.
Preprint · not peer-reviewed -
Behavioural scienceInfection and pandemics new
Canada's missing measles vaccine coverage figures are filled in by modelling
Researchers curated publicly available Canadian vaccine coverage data and modelled first-dose measles coverage by province, territory and age, then tested the same method against England's more complete records.
Preprint · not peer-reviewed -
Health todayHeart and stroke refines
GLP-1 agonists show no effect on atrial fibrillation in obese HFpEF patients
In 470 matched pairs of obese, non-diabetic patients with heart failure with preserved ejection fraction, GLP-1 receptor agonist treatment was not associated with lower atrial fibrillation incidence (HR 0.86, 95% CI 0.53-1.39), while all-cause mortality was lower (HR 0.42, 95% CI 0.23-0.75).
Peer-reviewed
