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Behavioural scienceDiet, exercise and sleep refines
Older adults walked 483 fewer steps after a day of higher fine particle exposure
In 67 UK adults aged 50-85, a day on which fine particle exposure ran 2.6 micrograms per cubic metre above the person's own average was followed by 483 fewer steps.
Preprint · not peer-reviewed -
Tomorrow's worldMedicine at a distance refines
Pacemakers after cardiac surgery carry higher later death and heart failure risk
Among 76 223 Swedish adults having cardiac surgery, the 2.8% given a pacemaker within 30 days had a higher adjusted risk of death and of heart failure admission over 6.8 years.
Peer-reviewed -
Tomorrow's worldChanging behaviour at scale refines
Stroke prevention texts raised cardiovascular check-ups, an online course did not
In an Australian trial of 941 adults aged 45 and over, self-reported visits for cardiovascular risk assessment were 41.3% in the text message arm as compared to 29.0% in control.
Peer-reviewed -
Health todayCancer new
Air pollution before surgery was associated with higher mortality in gastric cancer
In 4,441 patients operated on for stage I-III gastric cancer in China, each standard-deviation rise in PM2.5 before surgery carried 15% higher all-cause mortality and 31% higher gastric cancer mortality.
Peer-reviewed -
Tomorrow's worldMedicine at a distance refines
Exercise-based telerehabilitation raised peak oxygen uptake in cardiac patients
Telerehabilitation with exercise at its core raised peak oxygen uptake by 2.58 mL/kg/min in 13 randomised trials of 958 adults with cardiovascular disease, although the prediction interval crossed zero.
Peer-reviewed -
Tomorrow's worldA changing climate refines
Particulate matter shows no overall association with venous thromboembolism
An updated meta-analysis of 19 observational studies covering more than 4.5 million people found no significant overall association between long-term particulate exposure and venous thromboembolism, with a modest one appearing only among studies reporting in the same units.
Peer-reviewed -
Behavioural scienceAlcohol and drug use new
Brain-activity feedback from peers in recovery reduced craving in opioid use disorder
People with opioid use disorder were trained to match their frontal brain activity to that of peers further into recovery, and craving fell against sham feedback.
Preprint · not peer-reviewed -
Health todayHeart and stroke refines
Bempedoic acid cut LDL cholesterol by 17.5% in German lipid clinics
In 641 patients at seven German lipid clinics, mean LDL cholesterol fell by 17.5% three months after bempedoic acid was added, and 26.7% had stopped the drug by then.
Peer-reviewed -
Tomorrow's worldMedicine at a distance confirms
Telehealth-supported hepatitis C care was modelled to cost 69% less than specialist care
A cost model of the Cherokee Nation's hepatitis C programme, in which specialists advised primary care providers by video, put care at $1412 per patient against $4534 under specialist-based care.
Peer-reviewed -
Tomorrow's worldChanging behaviour at scale new
Smartphone CBT game improved depression symptoms and adherence against a waitlist
In 148 adults with residual symptoms on antidepressants, a smartphone CBT game with optional online modules improved depressive symptoms (d = 0.74) and medication adherence (d = 0.46) against a waitlist.
Peer-reviewed -
Health todayCancer new
A model puts daraxonrasib at $500,637 per quality-adjusted life year in pancreatic cancer
A cost-effectiveness model built from the RASolute 302 trial put daraxonrasib at $500,637 per quality-adjusted life year gained over chemotherapy, at a US price of $39,800 per 30 days.
Preprint · not peer-reviewed -
Tomorrow's worldInnovation in treatment refines
Self-guided lifestyle app lowered LDL-cholesterol by 3.9% more than usual care
In a pragmatic online trial of 278 adults with LDL-cholesterol above target, a self-guided lifestyle app lowered LDL by 3.9% more than usual care at six months.
Preprint · not peer-reviewed
